PB2540 a Novel fluorescent cannabinoid receptor (CB1) antagonist
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Tail Artery Adventitia. Red/Orange showsPB2540 binding to Vascular nerves. |
Tail Artery Adventitia. CB1 rich cell (red/orange) beside two alpha1-adrenoceptor rich (green) cells |
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Tail Artery Media. Patch of CB1 rich smooth muscle cells |
Tail Artery Media. Cross section of the wall. Smooth muscle cells in profile with adventitial cells above (cobtaining CB1 receptors) |
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Mesenteric artery smooth muscle cells. Co-localisation of CB1 and alpha1-ARs |
CB1 receptors on perivascular fat (left) and nerves (right) |
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3D views of CB1 binding (orange) on the perivascular fat shown above (right) |
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