This page presents a selection of our current and past work.
Davenport A & Daly CJ (2010). 'Editorial: Themed section: Imaging in pharmacology', in British Journal of Pharmacology, 159 (4) 735-737.
Daly CJ, Ross RA, Whyte J, Henstridge CM, Irving AJ & McGrath JC (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenergic and ‘cannabinoid-like’ receptors in small arteries. Br. J. Pharmacol., 159, 787-796.
Methven L, McBride M, Wallace GA & McGrath JC (2009a). The alpha(1B/D)-adrenoceptor knockout mouse permits isolation of the vascular alpha(1A)-adrenoceptor and elucidates its relationship to the other subtypes. Br J Pharmacol. Jun 30. [Epub early view]
Methven L, Simpson PC & McGrath JC (2009b). . alpha1A/B-Knockout mice explain the native alpha1D-adrenoceptor’s role in vasoconstriction and show that its location is independent of the other alpha1-subtypes. Br J Pharmacol, (In Press).
Shafaroudi MM, Daly CJ & McGrath JC. (2008) Multiple action sites of 2-AR agonist (UK14304) on different adrenoceptors in mice aorta. The Journal of Damghan University of Basic Sciences; 1(3) 111-122
Arribas SA, Daly CJ, Gonzalez MC & McGrath JC (2007) Imaging the vascular wall using confocal microscopy. J. Physiol. 584.1; 5-9 .
Morton, JS, Jackson VM, Daly CJ & McGrath JC (2007). Endothelium dependent relaxation in rabbit genital resistance arteries is predominantly mediated by endothelial-derived hyperpolarizing factor in females and nitric oxide in males. J Urol. Feb;177(2):786-91.
Morton JS, Daly CJ, Jackson VM, McGrath JC (2007). Alpha(1A)-Adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br J Pharmacol. Jan;150(1):112-20.
José M. González, Ana M. Briones, Beatriz Somoza, Craig J. Daly, Elisabet Vila, Barry Starcher, John C. McGrath, M. Carmen González, and Silvia M. Arribas.(2006) Postnatal alterations in elastic fiber organization precede resistance artery narrowing in SHR Am J Physiol Heart Circ Physiol 291: H804-H812.
McGrath JC & Daly CJ. The use of fluorescent ligands and proteins to visualise adrenergic receptors (2005) In: The Adrenergic Receptors in the 21st Century: The Receptor Series. Volume Editor: Dianne M. Perez: Series Editor: Kim Neve. Humana Press, Inc., Part 3; Chapter 6, pages 151-172
John Daniel Pediani, Janet Fraser Colston, Darren Caldwell, Graeme Milligan, Craig James Daly, and John Christie McGrath (2005) beta-arrestin Dependent Spontaneous alpha1a-Adrenoceptor Endocytosis causes Intracellular Transportation of alpha-blockers via Recycling Compartments. Molecular Pharmacology. 67; 992-1004.
Hamid S.A., Howe D., Campbell S., & Daly CJ. (2005) Visualisation of morphological changes in living intact human microvessels using confocal microscopy. Microvascular Research. Volume 69, Issue 3, May 2005, Pages 173-177
Daly CJ & McGrath JC (2005) The role of the alpha1B-adrenergic receptor in vascular structure and function. Hypertension. 45; e20-e21
Shafaroudi MM, McBride M, Deighan C, Wokoma A, Macmillan J, Daly CJ & McGrath JC (2005) Two knockout mouse models demonstrate that aortic vasodilatation is mediated via 2A-adrenoceptors located on the endothelium. J. Pharmacol Ther; 314; 804-810.
McGrath JC, Deighan C, Briones AM, Arribas SM, Vila E & Daly CJ. (2005) New aspects of vascular remodelling: the involvement of all vascular cell types. Experimental Physiology, 90.4: 469-475
Gonzalez JM et al., (2005) Influence of elastin on rat small artery properties. Experimental Physiology, 90.4; 463-468
Zacharia, J., Hillier, C., Tanoue, A., Tsujimoto, G., Daly C.J., McGrath, J.C. & MacDonald, A. Evidence from knockout mice for involvement of α1D-adrenoceptors in contraction of femoral resistance arteries. (2005). Br. J Pharmacol. British Journal of Pharmacology 146, 7; 942-951
Briones AM, Daly CJ, Jimenez-Altayo F, Martinez-Revelles S, Gonzalez JM, McGrath JC, Vila E (2005). Direct demonstration of 1- and evidence against 2- and 3- adrenoceptors, in smooth muscle cells of rat small mesenteric arteries. Br. J. Pharmacol. 146 (5) 679-691.